Practical computational genomics: one day workshop for college students
Overview: This workshop provides a glimpse of the emerging era of medical genomics. Given the rapid advances in genome sequencing technologies and the advent of massive datasets, careful research is needed to turn information into knowledge which can be put to use to improve the human condition. We will show how to use publicly available tools to understand genomics data, focusing on RNA expressions as part of disease research project. We will also discuss social implications of the medical revolution taking place. Our premise is that the Human Genome Project will soon become your own genome quest. No prior knowledge is needed. Bring your laptops.
Objectives: Participants will
1. gain essential knowledge in biomedical research.
2. become familiar with various online tools including the National Center for Biotechnology Information databases and software packages (no prior experience necessary).
3. learn to efficiently find scientific information on diseases and genes related to diseases.
4. gain an understanding of the shortcomings in current medical practices and the promise of the emerging field of medical genomics.
5. differentiate DNA, RNA, proteins, and their basic structure and function, identify RNA regions of a specific gene and understand healthy function, and understand miRNA function and RNA network.
Target audience: Graduate and undergraduate students.
Date: March 16, 2013
Time: 10:30 am – 4:30 pm
Location: Room 1230 Undergraduate Science Building, University of Michigan
You will receive email confirmation for the registration
10:15 am – 10:30 am
|10:30 am – 11:00 am||Genomics and Medicine |
Personalized medicine, genomics, and disease
Goal: understand shortcomings in current medical practices and the promise of the emerging field of medical genomics
|11:00 am – noon||Disease of focus |
Alzheimer’s, Autism, Breast Cancer, Type 1 Diabetes
Online resources about diseases – symptoms, treatment, genes, social impact
Groups will be formed to advocate for each disease, present about it and vote for one disease for the session
Goal: able to find scientific information related to disease of interest
noon – 12:15 pm
break and get lunch
|12:15 pm – 1:30 pm||DNA, RNA, Proteins Part I (Genes in Diseases) |
Lunch and lecture on basic genomics and common misconceptions
Each student chooses gene(s) related to the voted disease
Goal: 1. differentiate DNA, RNA, proteins, and their basic structure and function
2. understand RNA expression data to analyze them
1:30 pm – 1:45 pm
|1:45 pm – 2:55 pm||DNA, RNA, Proteins Part II (Genes in general) |
Computational research on chosen genes to suggest solutions for the voted disease
Goal: identify RNA regions of a specific gene and understand healthy function
2:55 pm – 3:05 pm
3:05 pm – 4:15 pm
Lecture on miRNA
Find regulating miRNAs for chosen genes to enhance the disease solutions
Teams (including one-person team) will identify combined solutions and present the solutions
An award to the best solution team
Goal: understand miRNA function and RNA network
4:15 pm – 4:30 pm